IRANDERMA 

Quiz: December 2003


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A 16-year old  girl presented with  a whitish plaque  over  the  nose  of  1 year  duration . It had  slowly progressed  to involve  the  upper  lip .extending  inside  the mouth  to  involve  the gum  pain  and  difficulty  in  chewing  and  brushing  of .teeth.  There  was no history of trauma , smoking or chewing tobacco .No other significant medical  or dental history . No family history.  Histopathology of  the skin lesion  showing hyperkertosis, focal  basal cell degeneration, Subepidermal hyalinization and  inflammatory cell infiltration. 

What's your diagnosis ?

 

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Diagnosis: Lichen Sclerosus Et Atrophicus (LSA)

LSA is an uncommon disease with unknown etiology. It usually begins in the form of ivory maculopapular lesions, later aggregates into  plaques and may resemble morphea. Mucosal involement occurs occasionally.

There is no effective therapy. Topical or intralesional steroids are sometimes helpful.

 

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